eGFR Calculator
The estimated glomerular filtration rate (eGFR) is the primary measure of kidney function used in clinical practice. It estimates how many millilitres of blood your kidneys filter per minute per 1.73 m squared of body surface area. This calculator uses the 2021 CKD-EPI creatinine equation, the current standard recommended by the National Kidney Foundation and American Society of Nephrology. The 2021 update removed race as a variable, ensuring equitable assessment for all patients. Enter your serum creatinine (mg/dL), age, and sex to calculate eGFR and determine your chronic kidney disease (CKD) stage per KDIGO guidelines.
2021 CKD-EPI formula (simplified)
eGFR = 142 x min(Cr/kappa, 1)^alpha x max(Cr/kappa, 1)^(-1.200) x 0.9938^Age x sex factor
Male: kappa=0.9, alpha=-0.302, sex factor=1.000
Female: kappa=0.7, alpha=-0.241, sex factor=1.012
Cr = serum creatinine in mg/dL
eGFR: frequently asked questions
What is eGFR?
Estimated glomerular filtration rate (eGFR) estimates how well your kidneys are filtering waste from your blood. It is reported in mL/min/1.73 m squared. A normal eGFR is 90 or above. The eGFR is calculated from serum creatinine, age, and sex using validated equations.
What CKD stages correspond to eGFR values?
KDIGO staging: G1 = eGFR 90+ (normal or high); G2 = 60-89 (mildly decreased); G3a = 45-59 (mild to moderate decrease); G3b = 30-44 (moderate to severe decrease); G4 = 15-29 (severely decreased); G5 = below 15 (kidney failure). CKD is diagnosed when abnormalities persist for 3 or more months.
Which eGFR equation does this calculator use?
This calculator uses the 2021 CKD-EPI creatinine equation (race-free version), which is now recommended by the National Kidney Foundation and American Society of Nephrology. It was updated in 2021 to remove race as a variable, improving equitable care for Black patients.
What is serum creatinine?
Creatinine is a waste product from normal muscle metabolism. Healthy kidneys filter creatinine from the blood into the urine. When kidney function declines, creatinine accumulates in the blood. Serum creatinine is the most commonly measured marker of kidney function and is used to estimate GFR.
What can cause a low eGFR?
Chronic kidney disease (diabetes-related nephropathy is the most common cause), acute kidney injury, severe dehydration, heart failure, certain medications (NSAIDs, aminoglycosides), and obstructive uropathy. A single low eGFR reading may not indicate CKD; repeated measurements over months are required for diagnosis.
Official sources
- National Kidney Foundation: GFR Calculator.
- National Institute of Diabetes and Digestive and Kidney Diseases: CKD Tests and Diagnosis.
Reviewed by the CalculatorHub team, edited by James Graham, 14 June 2026. See our methodology.