Framingham Risk Score Calculator
The Framingham general cardiovascular disease risk function estimates the 10-year probability of developing cardiovascular disease, including coronary disease, stroke, peripheral artery disease and heart failure. This calculator implements the published 2008 sex-specific Cox model, which combines age, total and HDL cholesterol, systolic blood pressure (treated or untreated), smoking and diabetes. The result is a percentage risk over the next decade. It was developed in adults aged 30 to 74 without prior CVD. Enter the values below. This is an educational estimate and not a diagnosis or treatment recommendation.
Framingham 2008 model
L = sum of (beta * ln(continuous)) + (beta * binary)
Risk = 1 - S0^exp(L - mean L)
Sex-specific betas, baseline survival S0 and mean L
Continuous terms log-transformed; result in percent
The model sums weighted log-transformed continuous variables (age, cholesterols, systolic pressure) and binary terms (treatment, smoking, diabetes), then applies the published baseline survival to give 10-year risk.
Using the estimate
- Output is the chance of cardiovascular disease over 10 years.
- Developed in adults aged 30 to 74 without prior CVD.
- Treated systolic pressure carries a higher coefficient than untreated.
- Smoking and diabetes are entered as present or absent.
- Risk thresholds for treatment are set by clinical guidelines.
Framingham risk: frequently asked questions
Which Framingham equation does this use?
It uses the 2008 Framingham general cardiovascular disease risk function published by D'Agostino and colleagues, which estimates 10-year risk of total CVD (coronary, cerebrovascular, peripheral artery disease and heart failure) using sex-specific Cox coefficients.
What inputs are required?
Age, sex, total cholesterol and HDL cholesterol (mg/dL), systolic blood pressure (mmHg), whether the systolic pressure is treated, current smoking status and diabetes status. All are entered below.
What is the age range for validity?
The 2008 function was developed in participants aged 30 to 74 years without prior cardiovascular disease. Estimates outside that range, or in people with existing CVD, are less reliable.
How is the risk percentage interpreted?
The output is the estimated probability of developing cardiovascular disease within 10 years. Lower is better. Risk categories and treatment thresholds are set by clinical guidelines and should be discussed with a clinician.
Is this a diagnosis?
No. It is a population-based risk estimate for education. It does not diagnose disease and does not replace individualized assessment by a qualified clinician.
Official sources
- National Heart, Lung, and Blood Institute (Framingham Heart Study): Framingham Heart Study resources.
- National Library of Medicine (NCBI): 2008 general CVD risk function literature.
Reviewed by the CalculatorHub team, edited by James Graham, 17 June 2026. See our methodology.